Yes! Through Preimplantation Genetic Screening (PGS) in conjunction with IVF, genetic and chromosomal abnormalities are detected in embryos. Only those embryos graded high quality are transferred to the mother’s uterus or cryopreserved for future Frozen Embryo Transfer (FET) procedures. High quality embryos identified through PGS lessen the chances of a failed pregnancy. Because advanced maternal age adversely affects the quality of a woman’s eggs, PGS is recommended in conjunction with IVF for patients over the age of 35. PGS is also recommended for women having multiple failed IVF cycles.
IVF Treatment to Prevent Miscarriages
Abnormalities in the number of chromosomes in the cells of an embryo is the most common cause of recurrent miscarriages. Embryos with chromosomal abnormalities may have the strength to attach to the uterine lining, but do not thrive into a fetus because of weakness.
Embryos thriving into a fetus and live birth normally have 23 pairs of chromosomes – a total of 46. When an embryo has too many – or too few – chromosomes, it suffers from an abnormality termed aneuploidy. A women over 35 has a greater chance of aneuploidy and miscarriage because of the natural decline in the quality of her eggs.
Detecting Chromosomal Abnormalities
Embryo chromosomal abnormalities can be detected through PGS. PGS will increase your chances of a successful pregnancy by screening and identifying chromosomal abnormalities in your embryos. Through PGS, cells are extracted from embryos developing in vitro prior to transfer. These cells are analyzed by an embryologist who will detect extra or missing chromosomes.
Recurrent miscarriage is medically defined as two or more consecutive pregnancy losses before 20 week gestation. Many couples delay in seeking medical help after experiencing two or more miscarriages. Don’t procrastinate obtaining help from a fertility specialist if you have experienced more than two miscarriage.
As a woman ages, her chance for chromosomal abnormalities in embryos increases. Low quality embryos result in:
- Low fertility rates
- High miscarriage rate
- High chance for birth defects
- A single cell is removed from the embryo
- The single cell’s genetic makeup is analyzed by the embryologist
- A decision is made as to the quality of the embryo
- Only high quality embryos are used in completion of a fresh IVF cycle
- Only high quality embryos are cryopreserved for a future FET procedures
Candidates for PGS:
- Women under 35 who have experienced two or more miscarriages – recurrent miscarriage
- Women who are over 35 and have experience one miscarriage
- Women who have had two or more unsuccessful IVF cycles
PGS offers hopeful parents-to-be the opportunity to:
- Screen out embryos with chromosomal abnormalities
- Improve their chance of a healthy birth
- Choose the gender of their baby
IVF Specialists to Help Prevent Miscarriages
It is important to work with a fertility care team having the experience required to design a customized IVF treatment plan meeting your personal needs. To schedule your initial consultation with one of the world renowned fertility specialists at New Hope Fertility NYC, click the icon below – or – call 917.525.5496.