Also known as 3-Parent IVF or 3-Person IVF, Human Egg Rejuvenation (H.E.R. IVF.) is the technique of using genetic material from three people to create a healthy embryo. The technical name for this breakthrough reproductive technology is Nuclear Transfer. The terms 3-Parent IVF and 3-Person IVF are somewhat misleading because the baby born from this technique only has two parents. H.E.R. IVF was initially designed as a technique to avoid inheritable DNA disorders like Mitochondrial Disease. Why is this important? Today, H.E.R. IVF is a proven solution for successfully treating advanced maternal age-related infertility.
H.E.R. IVF – 21st Century Revolutionary Reproductive Medicine
H.E.R. IVF is technology using an advanced egg environment-exchange protocol known as Spindle Nuclear Transfer.
- Designed to reverse the effects of age on human oocytes (eggs)
- Repairs certain cellular defects in eggs
The fertility specialists at New Hope Fertility Center pioneered the revolutionary H.E.R. IVF technique and produced the world’s first 3-Person IVF baby in 2016. See Dr. John Zhang’s 2016 ASRM Presentation covering technical and ethical questions about H.E.R. IVF.
Can H.E.R. IVF help you have a baby? Discover if you are a qualifying candidate for this remarkable technology through DARWIN LIFE, where future H.E.R. IVF candidacy evaluations will be performed on a case-by-case basis.
Basic requirements to be considered as a candidate for H.E.R. IVF.
- 32 to 47 years old
- 2 or more failed IVF cycles
- Regular monthly menstrual cycle
- Must be able to produce eggs
Common Question: Why do I need to produce my own eggs to qualify as a candidate for H.E.R. IVF? Answer: You must be able to produce your own eggs to transfer your DNA to the baby.
- The center of an egg’s cell is the nucleus
- The nucleus has the DNA required to form a human life
- The outside of the nucleus is a liquid – Cytoplasm
- Cytoplasm contain organelles – Mitochondria
- Mitochondria are the powerhouse of a cell responsible for body functions on a cellular level – examples: breathing, hearing, heart function
- Mitochondrial DNA is passed through conception maternally
Bottom Line: Through Nuclear Transfer, unhealthy mitochondrial DNA is left behind in the mother’s egg’s cytoplasm.
How Nuclear Transfer Works in Conjunction With IVF
Nuclear transfer is the process of transferring the nucleus of a woman’s poor quality egg into a donor’s healthy egg before it is fertilized in vitro.
- DNA-loaded spindles and their nuclear environment are removed from the intended mother’s oocyte (egg)
- The DNA-loaded spindles and their nuclear environment replace those inside a donor’s oocyte (egg)
- The replacement of the nuclear contents inside the donor’s egg reconstitutes it into a genetically identical and healthy donor egg
- The nuclear contents of the healthy donor egg is 98.9% identical
- The identical egg is then fertilized in vitro with the intended father’s sperm
- Once the resulting embryo has reached a prime stage of development in vitro, it is transferred to the intended mother’s uterus
Extremely Successful Egg Donor Program
New Hope Fertility Center offers an extremely successful egg donor program.
- Affordable donor packages
- World class donor support
- First rate support for intended parents
- Cutting edge IVF technologies
Our egg donor program has been created to facilitate the successful matching process between egg donors and recipient parents. Your personal egg donor coordinator will make the entire process simple by:
- Working closely with egg donors
- Guiding recipient parents through the matching process
- Coordinating the IVF medical staff and procedures
- Making the entire donor egg IVF process fast, easy, and safe!
You Can Have a Biological Connection to Your Child
Couples who have chosen to use an egg donor in conjunction with H.E.R. IVF can now have a biological bond to their child. Recipient mothers can carry a pregnancy to full term. The Nuclear Transfer treatment process takes only slightly longer than a Conventional IVF procedure and the number of cycles required varies case-by-case.
It is important to work with a fertility care team having the experience to accurately diagnose the underlying cause of your infertility and design a customized treatment plan meeting your specific medical and personal needs. To schedule your initial consultation with one of the fertility specialists at New Hope Fertility Center, click the icon below – or – call 917.525.5496.