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The IVF Fertility Blog

Embryology: The Study of Embryo Development

Embryo Development (2).jpgEmbryology plays a key role in IVF technology. Look: Embryology is the study of an embryo from the first stage of fertilization through fetal development. Why is this important? High quality embryos have the highest chance of implantation into a woman’s uterine lining resulting in a successful pregnancy. Cutting-edge IVF technology available at New Hope Fertility Center in NYC provides embryos culturing in vitro with an optimum environment for healthy development prior to fresh transfer and/or cryopreservation.

Embryology Roles in the IVF Process

  • HRSS – High Resolution Sperm Selection
  • ICSI – Intracytoplasmic Sperm Injection
  • Assisted Hatching
  • In Vitro Maturation
  • EmbryoScope


High Resolution Sperm Injection (HRSS). This is the technology providing embryologists with the ability to view sperm at 6000 x magnification using Differential Interference Contrast (DIC) microscopy. Through HRSS, an embryologist can view the physical details of each sperm – shape, size – looking for good morphological appearance. Normal chromosomes and less fragmentation in DNA are key factors playing a significant role in the quality of an embryo resulting from an egg’s fertilization with healthy sperm.


Intracytoplasmic Sperm Injection (ICSI) is an in vitro laboratory procedure helping to resolve male-factor infertility due to low sperm count or poor sperm quality. ICSI is a micromanipulation of fertilizing an egg by injecting a single sperm directly into the cytoplasm of a mature egg using a pipette (glass needle).

Assisted Hatching

A computer-assisted laser procedure – known as Assisted Hatching helps the mass of cells inside an embryo escape during transfer for better uterine lining implantation success. A tiny opening is made in the Zona Pellucida through a computer-assisted laser after the embryo has cultured for up to five days.

In Vitro Maturation

Through In Vitro Maturation (IVM) – also known as IVF/M or in vitro fertilization with maturation – immature eggs are retrieved for maturation in vitro and fertilization using ICSI.

EmbryoScope Technology

The rare opportunity for patients to benefit from EmbryoScope technology at New Hope Fertility Center provides time-lapsed information and monitoring of every embryo’s development without disruption of in vitro culturing.

Revolutionary Mini-IVF™

Our revolutionary Mini-IVF™ increases the chances of pregnancy without the need for large dosages of costly fertility medications used to produce an excessive number of eggs. Here’s the deal: The goal with a Mini-IVF™ protocol is to produce between 3 and 5 quality eggs per fresh cycle. The best part: Pregnancy success rates for Mini-IVF™ are comparable to Conventional IVF.

Mini-IVF™ Overview

Because lower dosages of fertility medications are prescribed to only produce 3 to 5 high quality eggs, the patient’s cost per Mini-IVF™ cycle is reduced. With a Mini-IVF™ protocol, the patient’s physical discomfort is lessened because her body is not forced into producing the 10 to 15 eggs reached in a Conventional IVF cycle.

Look: The Mini-IVF™ protocol in a nutshell.

  • A fertility medication regimen to produce 3 to 5 quality eggs
  • Cycle monitoring through ultrasound imaging and blood tests
  • Surgical egg retrieval
  • Fertilization of egg and sperm in vitro via (ICSI)
  • Culture and monitoring of embryo(s) via EmbryoScope technology
  • Grading and selection of quality embryos for fresh transfer
  • Grading and selection of quality embryos for future Frozen Embryo Transfer (FET) procedures
  • Single Embryo Transfer (SET)

Candidates for Mini-IVF™

Mini-IVF™ is the best treatment protocol for those women who have been:

  • Diagnosed with blocked or damaged Fallopian tubes due to endometriosis
  • Diagnosed with Polycystic Ovarian Syndrome (PCOS)
  • Diagnosed as having a risk of developing Ovarian Hyperstimulation Syndrome (OHSS)
  • Diagnosed with a low ovarian reserve due to endometriosis
  • Diagnosed with cancer and are about to undergo treatment

Mini-IVF™ has also become the preferred treatment protocol for:

  • Those patients who have failed multiple Conventional IVF cycles
  • Those patients suffering from male-factor infertility
  • Those patients wanting to reduce their costs of treatment
  • Those patients wanting to reduce their risk of multiple pregnancy
  • Those patients who don’t want to create excessive embryos due to religious reasons
  • Those patients who want to reduce their use of injectable medications because of an aversion to needles
  • Those patients who want to undergo another fresh IVF cycle immediately after a failed cycle

Celebrated Embryology Expertise

It is important to work with a fertility center having embryology expertise. We will design a customized IVF protocol meeting your personal needs. To schedule your initial consultation at New Hope Fertility Center click the icon below – or – call 917.525.5496.

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