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The IVF Fertility Blog

How is In Vitro Maturation Different Than Conventional IVF?

In vitro maturation (IVM) is among the newest techniques to help women who are doing IVF treatment.  Understanding what IVM is and how it differs from traditional in vitro fertilization protocols can help you to have informed discussions with your fertility care team.

Conventional IVF Process

With conventional IVF, fertility medication is given so that multiple eggs will mature inside the ovaries.  Once the eggs have reached maturity, they are harvested during an outpatient procedure.  Some of the eggs that are harvested are of a high quality and are suited for fertilization.  Others that are not mature are discarded. conventional ivf

IVM Process

When IVM is used, eggs are retrieved before they are fully matured.  The maturation process is done in a laboratory setting.  Once the eggs are mature, they can be fertilized and used in an IVF procedure.  There are four steps to the IVM process:

  • Fertility medication is administered in order to begin the maturation process.  Because stimulation is not needed for maturation, less medication is used than with a traditional protocol.
  • The eggs are retrieved before they are mature during an outpatient procedure. 
  • The retrieved eggs are then matured in an incubator in a laboratory
  • Once the eggs reach maturity, they are fertilized and the resulting embryos are monitored. The embryos may then be transferred back for implantation or frozen and stored for a future cycle.

Use of IVM

Due to medical issues, some women may benefit from using IVM during IVF.  These situations include:

  • When the fertility concern is shown to be a result of male infertility
  • Women who are at a greater risk of developing OHSS, including women who have PCOS
  • Women who are doing fertility preservation and need a shorter timeline due to other medical concerns

Speak with your fertility care team to determine if IVM can address your fertility concerns. For additional information on in vitro maturation, speak with a member of the New Hope Fertility Center team today.  Please click the link below to enter your information and New Hope will contact you, or simply call 212-517-7676.  Thank you.

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Topics: IVF, Conventional IVF

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