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The IVF Fertility Blog

How In Vitro Maturation (IVM) Increases IVF Pregnancy Success Rates

16 Cell Egg-1.jpgIVF in conjunction with egg maturation in a laboratory setting (IVF/M) increases a woman’s chances of using at least some of her immature eggs for in vitro fertilization and transfer. Look: Through In Vitro Maturation (IVF/M or IVM) technology, our fertility specialists are able to retrieve and bring some of your immature eggs to maturation in vitro. Why does this make a difference? Typically in past conventional IVF procedures, only mature eggs were surgically retrieved to be fertilized in vitro.

In Vitro Egg Maturation

A Conventional IVF procedure requires a woman to undergo multiple hormone injections to help produce 10 to 15 egg follicles as they reach maturity while they are still in her ovaries. In addition, the patient must endure multiple, regular ultrasounds and blood tests during a one month fresh IVF cycle.

The IVF/M procedure matures a woman’s eggs in vitro – in the laboratory – after they have been surgically retrieved in an immature stage. Here’s the deal: IVF/M requires fewer fertility medications and only a couple of ultrasound and blood tests during a typical one month cycle.

IVF/M cycle fertility medications are typically available in pill and suppository form. The best part? Because fertility medications are scaled back through the IVF/M process, the patient’s cost is reduced.

IVF/M (IVM) Process

IVF/M technology is used to retrieve and mature a woman’s immature eggs in a state-of-the-art controlled laboratory setting.

  • Immature eggs are surgically retrieved and placed in a petri dish containing a special maturation medium
  • The eggs are carefully monitored as they fully mature in vitro
  • Each individual egg is fertilized with a single sperm cell being injected into it – Intracytoplasmic Sperm Injection (ICSI)
  • The fertilized egg is monitored as it transforms into a quality embryo culturing in vitro for several more days
  • When the embryos have developed into a viable stage for transfer (blastocyst stage), they are ready for fresh transfer to the woman’s uterus – or – cryopreservation for future Frozen Embryo Transfer (FET) procedures
  • Only the highest quality embryos are selected for fresh transfer or cryopreservation

Candidates for IVF/M (IVM)

The candidates having the best pregnancy success rates using IVF/M (IVM) are:

  • Women with PCOS (polycystic ovarian syndrome)
  • Cancer patients who are sensitive to hormone therapy
  • Patients who want to reduce their risk of OHSS (ovarian hyperstimultion syndrome)
  • Young women who are able to produce a large number of egg follicles (10 to 15 per fresh cycle)
  • Women having a history of being able to produce a large number of egg follicles (10 to 15 per fresh cycle)
  • Women having an acceptable AMH (anti-mullerian hormone) level
  • Women who are at a healthy weight (BMI) – not obese

IVF/M (IVM) technology helps women who are not able to bring their eggs to maturity naturally. IVM harvests immature eggs and then matures them in a controlled laboratory setting before fertilization takes place in vitro.

IVF/M (IVM) Pregnancy Success Rates

Women under the age of 30 have the best pregnancy success chances using IVF/M – when eggs are retrieved before maturity. Pregnancy success rates are lower for women in their advanced maternal years – over 35.

Yearly ART data on IVF success rates is a rich source of information for potential IVF patients. This data gives patients an idea of their average chances of pregnancy success through IVF.

IVF success rates vary in the context of patient and treatment characteristics:

  • Age
  • Infertility diagnosis
  • History of previous pregnancies
  • History of previous miscarriages
  • Number of failed IVF cycles – fresh and frozen embryo transfers
  • Number of embryos transferred in a single cycle
  • Type of IVF procedure – Conventional IVF, Mini-IVF™ or Natural Cycle IVF™
  • IVF ancillary procedures used – ICSI, Assisted Hatching, In Vitro Maturation

You can find our IVF success rate outcomes in graphed data by clicking here.

IVF/M Experts

It is important to work with a fertility team having the clinical and research experience required to design a customized treatment plan meeting your personal medical needs. Schedule your initial consultation with the IVF/M Experts at New Hope Fertility Center.

Call 917.525.5496 – or – click the icon below.

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