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The IVF Fertility Blog

Natural Cycle IVF vs Conventional IVF

Natural Cycle IVF uses the technology of fertilizing an egg via in vitro, without using fertility medication.  A relatively new way of addressing infertility, natural cycle IVF provides an option for women who otherwise would have been unable to use IVF.  Understanding the difference between a natural and a normal IVF cycle can help you decide if a natural protocol is best for you.



With both normal and natural IVF cycles, women are monitored regularly using blood work and ultrasound:

  • In a normal cycle, the goal of monitoring is to evaluate both the number of follicles created and the size of those follicles.  Additionally, monitoring serves to evaluate the likelihood of a woman developing OHSS, Ovarian Hyper Stimulation Syndrome
  • In a natural cycle, the goal is to monitor the progress the egg a woman produces naturally.  There is no need for a follicle count or to look for indicators of OHSS.


For many fertility treatments, medication plays a key role in supporting a woman’s natural fertility:

  • During a normal IVF cycle women are prescribed injectable fertility medication.  These injections are done several times a day and are necessary to stimulate a woman’s body to produce multiple eggs.
  • Fertility medication is not used during a natural IVF cycle.

Comfort Level

There are a number of issues that can cause discomfort during IVF:

  • Discomfort during a normal IVF has a number of causes.  There is often discomfort associated with administering the medication.  Additionally, fertility medication can have a number of side effects. Furthermore, there may be pressure and discomfort associated with having a large number of follicles.
  • Discomfort is virtually eliminated during a natural cycle.  With the exception of the monitoring, a natural cycle is just like any other cycle for the woman.

Retrieval Process

The retrieval process for both normal and natural cycles is identical.  In both instances it is an outpatient procedure done under local anesthetic.  Because a larger number of eggs are retrieved during a normal IVF cycle, the procedure may take longer.

For additional information on Natural Cycle IVF, contact the expert fertility doctors at New Hope Fertility Center.  Please click the link below to enter your information and New Hope will contact you, or simply call 212-517-7676. Thank You.

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