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The IVF Fertility Blog

Next Generation Sequencing in Conjunction With IVF

Genetic screening is becoming an increasingly important part of the In Vitro Fertilization (IVF) process. Through the use of genetic screening, fertility experts are able to determine if an embryo has a genetic issue, such as a chromosomal abnormality or a genetic disease. The embryos with defects are not used, leaving only the healthiest embryos to be transferred during IVF or cryopreserved for future Frozen Embryo Transfers (FET). Using genetic screening decreases the likelihood of a miscarriage due to abnormalities in the embryo and ultimately increases the chance of delivering a healthy baby. New genetic screening provides an additional level of data to help researchers select the healthiest embryos in order to improve outcomes.

New Genetic Sequencing for IVF Cycles

Next Generation Sequencing (NGS), allows researchers to view the genetic makeup of an embryo at levels far exceeding that of previous testing methods. This new advancement in the fields of embryology and genetic research can significantly improve pregnancy outcomes by enhancing the knowledge embryologists employ while selecting embryos. NGS is significantly more accurate and faster than previous methods of genetic testing. This advancement in embryo screening can significantly increase pregnancy success for many women struggling to achieve and maintain a pregnancy to full term.

  • Women having poor egg quality
  • Women experiencing recurrent miscarriage
  • Women having multiple IVF failures


Impact of Genetic Testing on Embryos IVF

The most common cause of failed IVF cycles and miscarriage is believed to be chromosomal abnormalities. These occur during the early stages of an embryo's development. Many times, embryos with chromosomal abnormalities are unable to develop fully and result in the loss of a pregnancy. In some instances, the pregnancy is able to progress normally but the child is born with physical and mental birth defects. In women over 35, the most likely cause is poor egg quality. The likelihood of having eggs of low quality exponentially increases as a woman ages. The use of NGS can help these women and others with failed attempts, become pregnant.





More Helpful Resources From The Fertility Experts

Contact the fertility experts at New Hope Fertility Center if you’re struggling with infertility.

It is important to work with a fertility care team that understands which treatment methods are best for you, considering your specific medical issues. Personalized treatment plans offer the highest success rates and the best overall patient satisfaction. 

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Topics: IVF

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