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The IVF Fertility Blog

How PGS/NGS Can Help You Have a Baby

Pregnant Woman Fall (3)Your IVF pregnancy success chances can be increased by using cutting-edge genetic testing technology. PGS/NGS is the testing of an embryo’s overall chromosomal normalcy prior to being transferred to the patient’s uterus. Specifically, PGS/NGS identifies the most suitable and healthiest embryo to transfer to a woman’s uterus for hopeful implantation and successful fetal development. This cutting-edge technology detects chromosomal deficiencies in embryos – aneuploidy – an extra or missing chromosome.

PGS/NGS Increases IVF Pregnancy Success Rates Up To 30 Percent!

PGS/NGS at the universal blastocyst stage of an embryo’s development is recommended because the procedure can help increase the chances of a successful IVF pregnancy by 30 percent.

PGS/NGS in conjunction with IVF is recommended for:

  • Women over 37 who are undergoing IVF
  • Women who have had two or more unsuccessful IVF cycles
  • Women under 35 who have experienced two or more miscarriages – recurrent miscarriage
  • Women who are over 35 and have experience one miscarriage

Proven Increase in IVF Pregnancy Rates

State-of-the-art embryo biopsy techniques and genetics technologies have proven to increase IVF pregnancy rates. Through the medical marvel of PGS/NGS in conjunction with IVF, genetic and chromosomal abnormalities can be detected in embryos.

Genetic Testing For Low Quality Embryos to Make Informed Decisions

  • Only high quality embryos are transferred to the patient’s uterus
  • Only high quality embryos are cryopreserved for Future Embryo Transfer (FET) procedures

As a woman advances in age, the chance for low quality embryos increases.

Low quality embryos result in:

  • Low pregnancy success rates
  • High miscarriage rates
  • High chance for birth defects

PGS/NGS Procedure

PGS/NGS takes place in conjunction with IVF in a controlled laboratory setting. Approximately five (5) days – blastocyst stage – after fertilization of the patient’s eggs in vitro, a single cell is removed from each of the embryos developing.

  • A single cell is removed from the embryo by a highly skilled embryologist using a laser and a microscopic glass needle
  • The single cell’s genetic makeup is analyzed by the embryologist under a microscope
  • A decision is made as to the quality of each of the individual embryos
  • Only high quality embryos are used in completion of a fresh IVF cycle
  • Only high quality embryos are cryopreserved for future FETs

Benefits of PGS/NGS

The benefits of PGS in conjunction with IVF include:

  • Screening out embryos carrying a genetic disease
  • Predicting the risk of a genetic disease
  • Screening out abnormalities
  • Improving birth rates of healthy babies through IVF
  • Gender identification and selection

Next Generation Sequencing (NGS)

The latest technological innovation, Next Generation Sequencing (NGS) enhances how embryologists analyze and select quality embryos for transfer. Our embryologists give steadfast attention nurturing embryos as they develop in vitro.

Benefits of Next Generation Sequencing (NGS)

Quality embryos identified in vitro through NGS have the highest chance of implantation. Using NGS in conjunction with IVF, high quality embryos are transferred to the patient’s uterus for the best chance of a healthy, successful pregnancy.

Through NGS technology, you can identify the gender of your embryos in conjunction with your IVF procedure. Gender identification and selection is a natural byproduct of NGS technology.

NGS identifies the most suitable and healthiest embryo to transfer by detecting chromosomal deficiencies – aneuploidy – an extra or missing chromosome. NGS is set to replace Preimplantation Genetic Screening (PGS). NGS allows embryologists to view the genetic makeup of an embryo at levels far exceeding PGS technology.

  • Significant improvement in pregnancy outcomes
  • Enhancement of the knowledge embryologists employ while selecting embryos
  • Substantially more accurate and faster than PGS
  • Comprehensive results
  • Higher resolution
  • Detects more translocations
  • Reduced errors
  • Less costly than PGS

NGS may be conducted as a standalone test – or in conjunction with PGS – at a quicker completion rate. NGS also detects mosaicism – when an embryo’s cells exhibit a different chromosomal content.

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As a woman advances in age, the chance for chromosomal abnormalities in embryos increases. Low quality embryos result in:

  • Low pregnancy success rates
  • High miscarriage rates
  • High chance for birth defects

30% Increase in IVF Pregnancy Success Rates

Universal blastocyst-stage NGS is recommended because the procedure can help increase the chances of a successful pregnancy by 30 percent.

State-of-the-art embryo biopsy techniques and genetics technologies have proven to increase IVF pregnancy rates. Through the medical marvel of NGS in conjunction with IVF, genetic and chromosomal abnormalities can be detected in embryos.

After the gender of your embryos are identified through NGS, you can now choose the gender of the embryo(s) you transfer during a fresh IVF cycle – or – a future Frozen Embryo Transfer (FET) procedure. NGS technology allows you the ability to balance the gender of your children as you plan your family. This is known as Family Balancing. The accuracy of gender selection through NGS is greater than 99 percent.

EmbryoScope Technology

The rare opportunity for patients to benefit from EmbryoScope technology at New Hope Fertility Center provides time-lapsed information and monitoring of every embryo’s development without disruption of in vitro culturing.

NGS Technology in Conjunction with IVF

The fertility specialists at New Hope Fertility Center offer the highest success rates and best overall patient satisfaction through PGS/NGS technology in conjunction with IVF. To schedule your initial consultation click the ICON below – or – call 917.525.5496.

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