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The IVF Fertility Blog

IVF is the Preferred Fertility Treatment Post-IUI Failures

Muslim Woman With Ultrasound PicBecause IVF bypasses many common medical causes of infertility, it is the preferred treatment option for patients who have failed multiple IUIs. After thorough diagnostic testing has been performed to determine that your infertility is not structural, we will recommend the most promising treatment option. IUI – Intrauterine Insemination or artificial insemination – is often recommended as a first treatment option for unexplained infertility because it is the least invasive and most affordable. IUI boosts a woman’s pregnancy chances between 10 and 20 percent. Typically, IVF is not recommended until three to four IUI cycles have failed before IVF.

IUI Procedure

Once structural reproductive problems are ruled out, our fertility care team will design a customized IUI treatment plan around your personal needs.

IUI is the placement of a concentrated amount of motile sperm directly into a woman’s uterus. IUI is performed in the doctor’s office and requires no anesthesia – similar to a Pap smear. IUI treatment is perfectly timed with ovulation, whether or not fertility medications are used. The goal of IUI is to increase the number of sperm reaching a woman’s fallopian tubes to facilitate egg fertilization.

The production and release of multiple eggs is timed with concentrated sperm insemination.

  • The woman’s egg production is stimulated through the administration of oral fertility medications (Clomid or Femara)
  • Multiple egg follicles will be produced during one monthly cycle
  • The doctor regularly monitors the growth of the woman’s egg follicles through ultrasound imaging and blood tests
  • Once the egg follicles have reached a mature stage, ovulation is induced using a medication – the hCG trigger injection
  • The hCG injection is performed at home on a set time/date to facilitate the timing of ovulation and insemination of the sperm
  • On the day of the IUI procedure, a fresh sperm sample is collected (or a frozen sperm specimen is thawed) and prepared
  • Usually two IUIs are performed after the hCG trigger injection – between 12 and 36 hours – to increase the chance of pregnancy in a single cycle
  • Progesterone is prescribed daily via suppository to help prepare the woman’s uterine lining for successful implantation of an embryo
  • A pregnancy test is scheduled on a date prescribed by the doctor through a blood draw

Candidates for IUI

  • Same sex parents
  • Women under 35 who have been unable to get pregnant after one year of regular, unprotected sexual intercourse
  • Women over 35 who have been unable to get pregnant after six months of regular, unprotected sexual intercourse
  • Women who have failed timed intercourse because of irregular periods
  • Women using donated sperm
  • Women with mucus problems or other issues preventing sperm from reaching the uterus
  • Couples faced with male-factor infertility – low sperm count or poor motility

Moving on to IVF

After multiple failed IUIs, your fertility care team will discuss the pros and cons of continuing IUI attempts versus moving on to IVF.

IUI and IVF Fertility Specialists

We are a patient-focused fertility care team dedicated to helping our patients make the decision on when to move on from IUI to IVF treatment. To schedule your initial consultation with the fertility specialists at New Hope Fertility Center – click the icon below – or call 212.969.7422.

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